STRIDE was initially developed for UNIX and thoroughly tested on 3000 PDB files and many
different computers. For Macintosh I compiled STRIDE using the commercially available Metrowerks C
compiler. Two versions of the executable were prepared stored in BinHex format: mac68K.hqx for older 
Macs and powmac.hqx for PowerMacintosh.

NOTE ABOUT INTERFACE: STRIDE uses unix-style command line interface. Since Mac has no command
line, I had to use the SIOUX console IO library and modify main() (file stride.c) by adding 
just two lines in the very beginning:

---------------------------------------------------------

#include "stride.h"
#include <console.h>	/* First modification */

main()....

..............


argc = ccommand(&argv); /* Second modification */

---------------------------------------------------------

Note that these two lines are commented out in the source code, so if you want to recompile
the program, you will have to uncomment them.


Now if you click on the appropriate executable, a simple window pops up where you can type
all command line parameters exactly as under UNIX, for example:

1acp.brk -h -f1acp.str (see documentation).

After you press RETURN, the computer will freeze for 1 to 20 minutes, dependent on the PDB 
structure size, and then come back to life again. The PowerMac version is 10-20 times faster
on a PowerMac than mac68K.bin.

If you need a fancier, more Macintosh-like interface, you are more than welcome to develop
it. I am perfectly willing to cooperate, so please do not hesitate to contact me.

IMPORTANT NOTE: I am not a Mac expert and this is the first time I used a Mac for anything 
other than typing text. I have no idea about Mac's architecture. For example, the current
settings of minimal and typical memory required for the program and stack size were made 
essentially randomly. You might want to change these settings using the appropriate Mac 
utilities. Any feedback is welcome. Also, since I do not know how to run command scripts 
on Mac (is it possible?), the only way for me to test the program was to type command line 
parameters for every PDB file. I did it for about 100 randomly selected PDB structures and 
the results were correct. Still this is only a limited test...



Dmitrij Frishman
European Molecular Biology Laboratory
Meyerhofstr. 1, 69012 Heidelberg, Germany
tel. +49 -6221 - 387231
fax. +49 -6221 - 387517
frishman@embl-heidelberg.de